Rabbit anti-CYP17A1 Antibody

CYP17A1 Polyclonal Antibody

$200.00  
144-01373-50
+

Antigen Information

Accession Number:
  • P05093
Gene ID:
  • 1586
Gene Symbols:
  • CYP17A1
Protein Name & Synonyms:
CYP17A1, CPT7, CYP17, P450C17, S17AH, steroid 17-alpha-hydroxylase/17,20 lyase
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse
Clonality:
Polyclonal
Isotype:
IgG

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
57kDa
Observed MW
48kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human CYP17A1 (NP_000093.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of Jurkat cells, using CYP17A1 antibody (144-01373) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Western blot - CYP17A1 Polyclonal Antibody (144-01373)

No posts found

Write A Review

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.