Rabbit anti-EXOSC1 Antibody

EXOSC1 Polyclonal Antibody

$460.00  
144-10302-200
+

Antigen Information

Accession Number:
  • Q9Y3B2
Gene ID:
  • 51013
Gene Symbols:
  • EXOSC1
Protein Name & Synonyms:
EXOSC1, CGI-108, CSL4, Csl4p, SKI4, Ski4p, p13, exosome component 1
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human
Clonality:
Polyclonal
Isotype:
IgG

Background

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
21kDa
Observed MW
21kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human EXOSC1 (NP_057130.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using EXOSC1 antibody (144-10302) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Western blot - EXOSC1 Polyclonal Antibody (144-10302)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.

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