Rabbit Anti-GADD153 Antibody

Rabbit Anti-GADD153 Antibody, (100 ug)

168-10306
+

Antigen Information

Accession Number:
  • P35638
Protein Name & Synonyms:
GADD153

Antibody Specifications

Applications:
Western blotting (0.5-4 ug/ml), immunoprecipitation (10-20 ug/ml), and Immunohistochemistry (10-20 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 25 kDa GADD153 of human, mouse, and rat origins.
Concentration:
0.2 mg/ml
Host Species:
Rabbit

Synonyms

GADD153 , DDIT3 , 126337 ,P35638 , CEBPZ , CHOP , CHOP10 , GADD153 , MGC4154

Description

GADD153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. Expression of GADD153 is induced by a variety of cellular stresses, including nutrient deprivation and metabolic perturbations. GADD153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD153 dimers away from classical C/EBP binding sites. Thus GADD153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells.

Source

Immunogen
Synthetic peptide surrounding amino acid 124 of human GADD153
Purification
Affinity purified

Format

Physical Appearance
Colorless liquid
Formulation
100 µg (0.2 mg/ml) Protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Specificity

GADD 153

Storage

-20 °C. The shelf life is 12 months.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.