This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human HSPE1 (NP_002148.1).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using HSPE1 antibody (144-07437) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human gastric using HSPE1 antibody (144-07437) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of A549 cells using HSPE1 antibody (144-07437). Blue: DAPI for nuclear staining.
Expiration:
12 months from the date of shipment when stored properly.
