Rabbit Anti-Human Amyloid beta (N-term)

Rabbit Anti-Human Amyloid beta (N-term)

$420.00
DS-PB-02390
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Antigen Information

Protein Name & Synonyms:
Amyloid beta
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: , 1/200), Immunohistology - Paraffin
Preparation:
Antisera to amyloid beta (NT) were raised by repeated immunisations of rabbits with highly purified antigen.
Species Reactivity:
Human

Specificity

This product detects beta amyloid, an 87kDa member of the amyloid precursor protein family expressed in the adult brain. Beta amyloid is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer's disease (AD). Multiple transcript variants encoding several different isoforms have been found for this gene.

Mutations to the gene can also cause cerebroarterial amyloidosis (cerebral amyloid angiopathy).

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Serum - liquid
Format Type:
Serum

Preparation

Antisera to amyloid beta (NT) were raised by repeated immunisations of rabbits with highly purified antigen.

Immunogen:
Synthetic peptide corresponding to amino acid sequence 1-14 of human Amyloid Beta protein.
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.