Protein Name & Synonyms:
Immunohistology - Frozen, Western Blotting
This product detects a band of approximately 115kDa in HepG2 cell lysate.
This product recognizes CD107b, also known as LAMP-2, a single-pass type I membrane protein belonging to the LAMP family.
CD107b is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b varies between cell populations and the molecular weight of CD107b can vary between 92-120kD. This product migrates at 115 kDa in SDS page.
Studies suggest that CD107b may be involved in a range of cellular processes including leukocyte adhesion, protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome along with inter- and intracellular signal transduction. CD107b has also been implicated in tumour metastasis.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Antiserum to human CD107b was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
A peptide corresponding to an 17 amino acid sequence from near the carboxyl terminus of human CD107b.
0.02% Sodium Azide (NaN3)