Protein Name & Synonyms:
CD257
Applications:
Western Blotting
Concentration (lot specific):
IgG concentration 0.5 mg/ml
Preparation:
Antisera to CD257 (BAFF) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.
Species Reactivity:
Human, Mouse and rat
This product recognizes CD257 (also known as BLyS, BAFF, TALL-1 and THANK), a novel member of the tumor necrosis factor (TNF) superfamily. CD257 and its receptor TACI/BCMA are involved in the development of autoimmune diseases.
CD257 has been shown to activate NFkB and JNK (c-jun N-terminal kinase) and induce apoptosis.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Antisera to CD257 (BAFF) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.
Immunogen:
Peptide corresponding to amino acids 254-269 of human CD257 (BAFF).
Expiration:
12 months from the date of shipment when stored properly.