Rabbit Anti-Human CD261 (N-term)

Rabbit Anti-Human CD261 (N-term) (0.1 mg)
CODE:  DS-PB-00427

Antigen Information

Protein Name & Synonyms:
CD261
Target Species:
  • Human

Antibody Specifications

Applications:
Western Blotting
Concentration:
IgG concentration 0.5 mg/ml
Preparation:
Antisera to CD261 (DR4) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Species Reactivity:
Human

Specificity

This product recognizes the 57kD apoptosis related protein designated DR-4 (death receptor 4), also known as CD261.

DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL, and thus DR-4 has also been called TRAIL-RI. DR4 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to CD261 (DR4) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.

Immunogen:
Peptide from N-terminus of human CD261 (DR4)
Preservative:
0.02%Sodium Azide