Rabbit Anti-Human CYP3A4

Rabbit Anti-Human CYP3A4

DS-PB-00588
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Antigen Information

Protein Name & Synonyms:
CYP3A4
Target Species:
  • Human

Antibody Specifications

Applications:
Functional Assays, Western Blotting
Preparation:
Antisera to human CYP3A4 were raised by repeated immunisation of rabbits with highly purified antigen.
Species Reactivity:
Human

Specificity

This product recognizes human cytochrome p450 3A4 (CYP3A4). P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. This product is a neutralizing antibody which is a specific and potent inhibitor of CYP3A4.

Storage/Stability

Store at -20 °C. Ship at +4 °C.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Serum - liquid
Format Type:
Serum

Preparation

Antisera to human CYP3A4 were raised by repeated immunisation of rabbits with highly purified antigen.

Immunogen:
Purified human CYP3A4 expressed in E.Coli
Preservative:
None Present

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.