Rabbit Anti-Human DcR3 (C-term.)

Rabbit Anti-Human DcR3 (C-term.)

$427.00
129-10228
+

Antigen Information

Protein Name & Synonyms:
DcR3
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin, Western Blotting
Concentration:
0.5 mg/ml
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat

This product detects a band of approximately 33kDa in human heart lysate.

Specificity

This product recognizes the amino terminal of human DcR3, otherwise known as Decoy Receptor 3, a 33kDa member of the tumour necrosis factor receptor superfamily.

DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis.

DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung. It may also be found in fetal lung, brain and liver and is highly expressed in several primary tumours from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antiserum to human DcR3 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.

Immunogen:
A peptide corresponding to amino acids near the amino-terminus of human DcR3 precursor.
Preservative:
0.02% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.