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770-729-2992
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Product Specifications
Size:
0.1 ml
Protein Information
Protein Name & Synonyms:
Dopamine Transporter
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, Western Blotting
Preparation:
Antisera to human dopamine transporter (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Species Reactivity:
Human, Monkey, Human and Mouse
This product detects a band of approximately 88kDa in human caudate cell lysates.
Specificity
This product recognizes an epitope within the C-terminal region (CT) of dopamine transporter (DAT), also known as solute carrier family 6.
DAT is principally expressed in the presynaptic membrane of dopaminergic nerve terminals, where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availability of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine.
The reuptake of dopamine by DAT is inhibited by psychostimulants such as cocaine and amphetamine.
DAT is principally expressed in the presynaptic membrane of dopaminergic nerve terminals, where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availability of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine.
The reuptake of dopamine by DAT is inhibited by psychostimulants such as cocaine and amphetamine.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
10mM HEPES pH7.5
150mM NaCl
150mM NaCl
Format Type:
Purified
Preparation
Antisera to human dopamine transporter (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen:
Keyhole limpet hemocyanin conjugated synthetic peptide corresponding to the C-terminus region (CT) of human dopamine transporter.
Preservative:
| 0.09% | Sodium Azide |
| 0.01% | Bovine Serum Albumin |
| 50% | Glycerol |
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
