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770-729-2992
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Product Specifications
Size:
0.1 mg
Protein Information
Protein Name & Synonyms:
DR3
Target Species:
- Human
Antibody Specifications
Applications:
Western Blotting
Concentration (lot specific):
IgG concentration 1.0mg/ml
Preparation:
Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Species Reactivity:
Human
Specificity
This product recognizes a 59kD apoptosis related protein designated DR3 (death receptor-3).
DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).
The ligand for DR3 has very recently been identified and has been termed Apo-3L.
DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.
DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).
The ligand for DR3 has very recently been identified and has been termed Apo-3L.
DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.
Storage/Stability
Store at +4 °C for one month or at -20 °C for longer.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Immunogen:
Peptide sequence QGGTRSPRCDCAGDFH from amino terminus of human DR3
Preservative:
| 0.02% | Sodium Azide |
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
