Rabbit Anti-Human DR3 (N-term)

Rabbit Anti-Human DR3 (N-term)

$420.00
DS-PB-00666
+

Antigen Information

Protein Name & Synonyms:
DR3
Target Species:
  • Human

Antibody Specifications

Applications:
Western Blotting
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Species Reactivity:
Human

Specificity

This product recognizes a 59kD apoptosis related protein designated DR3 (death receptor-3).

DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).

The ligand for DR3 has very recently been identified and has been termed Apo-3L.

DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.

Storage/Stability

Store at +4 °C for one month or at -20 °C for longer.

This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.

Immunogen:
Peptide sequence QGGTRSPRCDCAGDFH from amino terminus of human DR3
Preservative:
0.02%Sodium Azide

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.