Rabbit Anti-Human ERK1 / MAPK3

Rabbit Anti-Human ERK1 / MAPK3

DS-PB-00721
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Antigen Information

Protein Name & Synonyms:
ERK1 / MAPK3
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to ERK1 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human

Specificity

This product detects extracellular signal regulated kinase 1 (ERK1), a 45kD protein involved in the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. ERK1 is a member of the MAP kinase (MAPK) family, and is activated by MAP/ERK kinase 1 (MEK1) and MEK2.

A number of recent studies in models of cerebral ischemia, brain trauma and neurodegenerative diseases implicate a detrimental role for ERK1/2 signalling during oxidative neuronal injury.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to ERK1 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Synthetic peptide: Internal domain of human ERK1.
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.