Rabbit Anti-Human ERR gamma (N-term)

Rabbit Anti-Human ERR gamma (N-term)

$571.00
DS-PB-02599
+

Antigen Information

Protein Name & Synonyms:
ERR gamma
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to human ERR gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human, Mouse, Rat

Specificity

This product detects estrogen-related receptor gamma (ERR gamma), a member of the nuclear hormone receptor superfamily. The fasting-induced coactivator protein PGC-1α has been shown to activate the ERR gamma, and together these proteins have a major role in the regulation of ERR alpha gene expression and energy homeostasis.

ERR gamma and alpha are co-expressed in high energy demanding tissues such as skeletal muscle heart and kidney, and have been suggested to function in their differentiation.

ERR gamma has also been shown to be over-expressed in breast tumours, and has been suggested to be a potential biomarker for favourable clinical course and hormonal sensitivity.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to human ERR gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Synthetic peptide: N-terminal domain of human ERR gamma, conjugated to Keyhole Limpet Hemocyanin (KLH).
Preservative:
0.1%Sodium Azide (NaN3)

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.