Protein Name & Synonyms:
FEN1
Applications:
Immunoprecipitation, Western Blotting
Concentration (lot specific):
IgG concentration 1.0 mg/ml
Preparation:
Antisera to human FEN1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human
This product detects a band of approximately 42kD in HeLa cell lysates.
This product is specific for human flap structure-specific endonuclease 1 (FEN1).
FEN1 is a member of the XPG/RAD2 endonuclease family which has an important role in lagging strand DNA synthesis and base excision repair. It is hypothesised that FEN1 may play a role in the inhibltion of triplet repeat expansion.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
TRIS-citrate/Phosphate buffered saline
Antisera to human FEN1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen:
Synthetic peptide corresponding to a region within the N terminal domain of human FEN1 (locus link ID 2237)
Expiration:
12 months from the date of shipment when stored properly.