Rabbit Anti-Human FEN1

Rabbit Anti-Human FEN1
CODE:  DS-PB-00756

Antigen Information

Protein Name & Synonyms:
FEN1
Target Species:
  • Human

Antibody Specifications

Applications:
Immunoprecipitation, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Preparation:
Antisera to human FEN1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human

This product detects a band of approximately 42kD in HeLa cell lysates.

Specificity

This product is specific for human flap structure-specific endonuclease 1 (FEN1).

FEN1 is a member of the XPG/RAD2 endonuclease family which has an important role in lagging strand DNA synthesis and base excision repair. It is hypothesised that FEN1 may play a role in the inhibltion of triplet repeat expansion.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
TRIS-citrate/Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to human FEN1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Synthetic peptide corresponding to a region within the N terminal domain of human FEN1 (locus link ID 2237)
Preservative:
0.09%Sodium Azide