Rabbit Anti-Human Glycogen Phosphorylase BB

Rabbit Anti-Human Glycogen Phosphorylase BB

DS-PB-02619
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Antigen Information

Protein Name & Synonyms:
Glycogen Phosphorylase BB
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin
Concentration:
IgG concentration 1.0 mg/ml
Preparation:
Antisera to human brain glycogen phosphorylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human

Specificity

This product detects brain glycogen phosphorylase, a regulatory enzyme which catalyses the rate-determining step in glycogen degradation. Mammalian glycogen phosphorylase is found as three major isozymes including muscle (GPMM), liver (GPLL), and brain (GPBB), which can be distinguished by their structural and functional properties as well as by the tissues in which they are expressed.

GPBB is thought to function in the release of emergency glucose during stress, and in embryogenesis where it is the predominant isozyme. GPBB is also expressed in the early stages of gastric and colorectal cancers.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to human brain glycogen phosphorylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Synthetic peptide: internal domain of human brain glycogen phosphorylase, conjugated to Keyhole Limpet Hemocyanin.
Preservative:
0.09% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.