Rabbit Anti-Human iASPP

Rabbit Anti-Human iASPP

$420.00
DS-PB-02628
+

Antigen Information

Protein Name & Synonyms:
iASPP
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: 1/1000, 1/5000), Western Blotting
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to human iASPP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Species Reactivity:
Human

This product detects a bands of approximately 100 and 50kDa corresponding to iASPP isoforms 1 and 2 respectively.

Specificity

This product detects human inhibitor of apoptosis stimulating protein of p53 (iASPP), which plays a central role in regulation of apoptosis and transcription via its interaction with NFkB and p53 proteins. At present, the iASPP gene is thought to encode three isoforms; isoform 1 is predominantly located in the cytoplasm, whilst isoforms 2 and 3 are nuclear proteins. iASPP is highly expressed in the heart, placenta and prostate.

iASPP has been shown to have oncogenic properties in human breast carcinomas.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to human iASPP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Immunogen:
Synthetic peptide corresponding amino acids 780-797 of human iASPP (isoform 1) protein.
Preservative:
0.09% Sodium Azide (NaN3)

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.