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Product Specifications
Size:
0.1 mg
Protein Information
Protein Name & Synonyms:
IL-16
Target Species:
- Human
Antibody Specifications
Applications:
ELISA (dilution: 0.1, 0.2ug/ml), Functional Assays, Western Blotting
Concentration (lot specific):
IgG concentration 1.0mg/ml
Preparation:
Antisera to human IL-16 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by antigen affinity chromatography.
Reconstitution:
Reconstitute with 0.1ml distilled water.For long term storage the addition of 0.09% Sodium Azide is recommended.
Species Reactivity:
Human
For functional studies do not add Azide.
Specificity
This product is specific for human IL-16 (Interleukin-16), originally known as leucocyte chemoattractant factor (LCF), an immunomodulatory cytokine which induces the chemotaxis of CD4 expressing T cells, eosinophils and monocytes and is produced constitutively by T cells, eosinophils, dendritic cells, fibroblasts and neuronal cells.
The biologically active form of IL-16 is generated by enzymatic cleavage of the IL-16 precursor (pro-IL16), producing a peptide corresponding to the 121 amino acid C-terminal portion. Further properties attributed to IL-16 include the induction of MHC class II and IL-2 receptor (IL-2R) expression, and several studies have indicated a role for IL-16 in inflammatory processes.
The biologically active form of IL-16 is generated by enzymatic cleavage of the IL-16 precursor (pro-IL16), producing a peptide corresponding to the 121 amino acid C-terminal portion. Further properties attributed to IL-16 include the induction of MHC class II and IL-2 receptor (IL-2R) expression, and several studies have indicated a role for IL-16 in inflammatory processes.
Storage/Stability
Prior to reconstitution store at +4 °C. Following reconstitution store at -20 °C.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Format
Supplied as:
Purified IgG - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 0.1ml distilled water.
For long term storage the addition of 0.09% Sodium Azide is recommended.
For long term storage the addition of 0.09% Sodium Azide is recommended.
Format Type:
Purified
Preparation
Antisera to human IL-16 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by antigen affinity chromatography.
Immunogen:
Recombinant human IL-16
Preservative:
None present
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
