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Product Specifications
Size:
50 µg
Protein Information
Protein Name & Synonyms:
IL-19
Target Species:
- Human
Antibody Specifications
Applications:
ELISA (dilution: 0.1, 0.2ug/ml), Western Blotting
Concentration (lot specific):
IgG concentration 0.1mg/ml after reconstitution.
Preparation:
Antisera to human IL-19 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Reconstitution:
Reconstitute with 0.5ml sterile PBS containing 0.1% Bovine Serum Albumin.. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Species Reactivity:
Human
Specificity
This product is specific for human IL-19 (interleukin-19), a 153 amino acid secreted helical cytokine belonging to the IL-10 family of regulatory cytokines, which is preferentially expressed in monocytes, but also expressed in B cells, and up-regulated in monocytes stimulated with lipopolysaccharide (LPS) or granulocyte-macrophage colony-stimulating factor (GM-CSF).
IL-19 has been implicated as a regulator in the inflammatory response and signals through binding to a receptor complex (IL-20R) composed of the IL-20R1 (CRF2❏❏8) and IL-20R2 (CRF2❏❏11 ) chains, which leads to the activation of signal transducer and activator of transcription 3 (STAT3).
IL-19 has been implicated as a regulator in the inflammatory response and signals through binding to a receptor complex (IL-20R) composed of the IL-20R1 (CRF2❏❏8) and IL-20R2 (CRF2❏❏11 ) chains, which leads to the activation of signal transducer and activator of transcription 3 (STAT3).
Storage/Stability
Prior to reconstitution store at +4 °C.
After reconstitution store at -20 °C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Format
Supplied as:
Purified IgG conjugated to Biotin - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 0.5ml sterile PBS containing 0.1% Bovine Serum Albumin.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Preparation
Antisera to human IL-19 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen:
Recombinant human IL-19
Preservative:
None present
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
