Protein Name & Synonyms:
Immunohistology - Paraffin, Western Blotting
Human, Mouse, Rat
This product detects a band of approximately 33kDa in K562 cell lysates.
This product recognizes human Mortality Factor 4 (MORF4), known also as SEN1 and cellular senescence-related protein 1.
MORF4 is a nuclear localized protein possessing transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that are believed to allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription co-repressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Antiserum to human MOR4 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
A peptide corresponding to an 18 amino acid peptide from near the amino terminus of human MORF4.
0.02% Sodium Azide (NaN3)