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Antigen Information
Protein Name & Synonyms:
Osteocalcin
Target Species:
- Human
Antibody Specifications
Applications:
ELISA (dilution: 1/30, 1/300)
Concentration:
5.0 mg/ml
Species Reactivity:
Human
Specificity
This product is specific for human osteocalcin.
Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa) made by osteoblasts, that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget❏'s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa) made by osteoblasts, that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget❏'s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Synthetic peptide corresponding to amino acids 37 - 49 of human osteocalcin conjugated to Keyhole limpet Haemocyanin.Peptide sequence: GFQEAYRRFYGPV
Preservative:
0.09% Sodium Azide (NaN3)
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
