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Antigen Information
Protein Name & Synonyms:
SMAC/DIABLO
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Paraffin, Western Blotting
Concentration:
IgG concentration 0.5 mg/ml
Preparation:
Antisera to human Smac/DIABLO were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human, Mouse, rat
Specificity
This product recognizes the C-terminal region of human Smac/DIABLO. Inhibitors of apoptosis proteins (IAP's) block cell death by caspase inhibition. X-linked inhibitor of apoptosis (XIAP) is a member of the IAP family. Smac/DIABLO is expressed in a variety of tissues and has been identified as a negative regulator of XIAP.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Antisera to human Smac/DIABLO were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen:
Synthetic peptide corresponding to amino acids 225-239 of human Smac/DIABLO
Preservative:
| 0.02% | Sodium Azide |
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
