Rabbit Anti-Human T-Cadherin

Rabbit Anti-Human T-Cadherin (0.1 mg)

$420.00
DS-PB-01914
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Antigen Information

Protein Name & Synonyms:
T-Cadherin
Target Species:
  • Human

Antibody Specifications

Applications:
Immunofluorescence, Western Blotting
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to Cadherin 13 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Species Reactivity:
Human, Mouse

This product detects a band/s of approximately 78kDa in 3T3 cell lysates.

Specificity

This product recognizes human Cadherin 13, a 78 kDa, calcium-dependent, glycoprotein. While Cadherin 13 is a member of the cadherin family, it lacks their conserved cytoplasmic region, being instead anchored to the plasma membrane via glycosylphosphatidylinositol linkage. It is expressed in the heart and CNS with the exception of the cerebellum and spinal cord.

Cadherin 13 is classified as a cell-cell adhesion molecule, although it is likely that it❏'s role is in signalling and not physical adhesion. It is involved in regulating low-density lipoprotein-initiated cell proliferation, keratinocyte proliferation, neural cell growth and may play a role in metabolic regulation. Cadherin 13 protects endothelial cells from oxidative stress-induced apoptosis and may contribute to progression of vascular disorders such as atherosclerosis, restenosis and tumour angiogenesis.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to Cadherin 13 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Immunogen:
Synthetic peptide corresponding to N-terminus of human Cadherin 13.
Preservative:
0.02%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.