Rabbit Anti-Human TIMP-1

Rabbit Anti-Human TIMP-1

DS-PB-01963
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Antigen Information

Protein Name & Synonyms:
TIMP1
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: 5 ug/ml, 10 ug/ml), Immunohistology - Paraffin, Western Blotting
Concentration:
1.0 mg/ml
Species Reactivity:
Human, Bovine, Ferret, Horse, Rabbit, Rat, Sheep

Specificity

This product reacts with native and denatured TIMP-1, as well as TIMP-1 in and out of enzyme/inhibitor complex. This antibody is not neutralizing.

TIMP-1 is expressed by a wide range of cells including microvascular endothelial cells, smooth muscle cells, mesangial cells and some fibroblasts. TIMP-1 inhibits matrix metalloproteinase activity by forming complexes via reversible non covalent binding. It is reported to be involved in the control of angiogenesis and tumour growth.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Human tissue inhibitor of metalloproteinase 1 (TIMP-1)
Preservative:
0.02%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.