Rabbit Anti-Human Uncoupling Protein 4

Rabbit Anti-Human Uncoupling Protein 4

DS-PB-02052
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Antigen Information

Protein Name & Synonyms:
Uncoupling Protein 4
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA, Western Blotting
Concentration:
IgG concentration 5.0 mg/ml
Immunogen Sequence:
KSSTDCLIQAVQG
Species Reactivity:
Human

In reduced blots on bovine brown adipose tissue homogenates, this antibody recognizes specific bands at 34 & 44kD and other bands at 50 & 60 kD that can be blocked with KLH.

Specificity

This product recognizes Uncoupling Protein 4.

UCP4 facilitates the dissipation of heat across the inner mitochondrial membrane, by leaking protons across the membrane and uncoupling oxidative phosphorylation from ATP synthesis. UCP4 is understood to be involved in thermoregulatory heat production and metabolism in brain.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Synthetic peptide corresponding to the amino acids 271 - 283 of the native molecule conjugated to Keyhole Limpet Haemocyanin.
Preservative:
0.09% Sodium Azide (NaN3)
Amino Acid Sequence:
KSSTDCLIQAVQG

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.