Rabbit Anti-Human VEGFR2

Rabbit Anti-Human VEGFR2

DS-PB-02108
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Antigen Information

Protein Name & Synonyms:
VEGFR2
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin
Concentration:
IgG concentration 0.5 mg/ml
Preparation:
Antisera to human VEGF receptor 2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human

Specificity

This product detects vascular endothelial growth factor receptor 2 (VEGFR2), a member of the tyrosine kinase family that plays an essential role in transducing the major signals for angiogenesis. VEGFR2 has also been implicated in embryonic development, wound healing, cell proliferation, migration and differentiation.

VEGFR2 is expressed mostly on vascular endothelial cells, and is expressed on a subpopulation of hematopoietic cells which might be the progenitor for endothelial cells.

Mutated forms of VEGFR2 have been implicated in cancer and diabetic retinopathy, where it results in pathological angiogenesis.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to human VEGF receptor 2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Synthetic peptide: internal domain of human VEGF receptor 2, conjugated to Keyhole Limpet Hemocyanin (KLH).
Preservative:
0.1%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.