Rabbit Anti-Human XIAP (C-term)

Rabbit Anti-Human XIAP (C-term)

$420.00
DS-PB-02099
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Antigen Information

Protein Name & Synonyms:
XIAP
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin, Western Blotting
Concentration:
IgG concentration 1 mg/ml
Preparation:
Antisera to human XIAP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human, Mouse

Specificity

This product is specific for human X-chromosome linked inhibitor of apoptosis (XIAP).

XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs).

Regulators of XIAP activity include XAF-1 and Smac.

This product detects a band of approximately 57KDa in human kidney lysates.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to human XIAP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Synthetic peptide corresponding to a thirteen amino acid sequence with the C-terminal region of human XIAP.
Preservative:
0.02%Sodium Azide

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.