Protein Name & Synonyms:
IDI1, IPP1, IPPI1, isopentenyl-diphosphate Delta-isomerase 1
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 225-284 of human IDI1 (NP_004499.2).
Store at -20°. Avoid freeze / thaw cycles.