Rabbit anti-IL17RB Antibody

IL17RB Polyclonal Antibody

$200.00
144-10147-50
+

Antigen Information

Accession Number:
  • Q9NRM6
Gene ID:
  • 55540
Gene Symbols:
  • IL17RB
Protein Name & Synonyms:
IL17RB, CRL4, EVI27, IL17BR, IL17RH1, interleukin-17 receptor B
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse, Rat
Clonality:
Polyclonal Antibodies
Isotype:
IgG

Background

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Dilutions

WB 1:1000 - 1:4000

Format

Calculated MW
31kDa/55kDa
Observed MW
75kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195.2).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using IL17RB antibody (144-010147) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
Western blot - IL17RB Polyclonal Antibody (144-010147)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.