Protein Name & Synonyms:
IL17RB, CRL4, EVI27, IL17BR, IL17RH1, interleukin-17 receptor B
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
WB 1:1000 - 1:4000
Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195.2).
Western blot analysis of extracts of various cell lines, using IL17RB antibody (144-010147) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.