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Rabbit anti-JAG1 Antibody

JAG1 pAb

$200.00  
144-62453-50
+

Antigen Information

Accession Number:
  • P78504
Gene ID:
  • 182
Gene Symbols:
  • JAG1
Protein Name & Synonyms:
JAG1, AGS, AGS1, AHD, AWS, CD339, HJ1, JAGL1, jagged 1
Target Species:
  • Human

Antibody Specifications

Applications:
WB, IF
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse
Isotype:
IgG

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
116kDa/133kDa
Observed MW
160kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 34-180 of human JAG1 (NP_000205.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.