Protein Name & Synonyms:
JAG1, AGS, AGS1, AHD, AWS, CD339, HJ1, JAGL1, jagged 1
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 34-180 of human JAG1 (NP_000205.1).
Store at -20°. Avoid freeze / thaw cycles.