This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Dilutions
WB 1:500 - 1:1000 IHC 1:50 - 1:100
Format
Calculated MW
130kDa
Observed MW
115kDa
Immunogen
A synthetic peptide of human JAK2
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using JAK2 antibody (144-07694) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human stomach using JAK2 antibody (144-07694) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using JAK2 antibody (144-07694) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.
