Rabbit anti-LZTS2 Antibody

LZTS2 Polyclonal Antibody

$200.00
144-60721-50
+

Antigen Information

Accession Number:
  • Q9BRK4
Gene ID:
  • 84445
Gene Symbols:
  • LZTS2
Protein Name & Synonyms:
LZTS2, LAPSER1, leucine zipper tumor suppressor 2
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal Antibodies
Isotype:
IgG

Background

The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
72kDa
Observed MW
75kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 470-669 of human LZTS2 (NP_115805.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using LZTS2 antibody (144-60721) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
Western blot - LZTS2 antibody (144-60721)

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.