Rabbit Anti-N. meningitidis

Rabbit Anti-N. meningitidis

$420.00
DS-PB-01407
+

Antigen Information

Protein Name & Synonyms:
N. meningitidis
Target Species:
  • Bacterial

Antibody Specifications

Applications:
ELISA, Immunofluorescence
Concentration:
IgG concentration 4 mg/ml
Species Reactivity:
Bacterial

Specificity

This product reacts with Neisseria meningitidis serogroups A, B and C and is thought to recognize all antigens. Other serogroups have not been tested.

N. meningitidis is a gram-negative bacteria that is the causative agent of meningitis. There are 13 known significant serogroups that are classified according to the structure of their polysaccharide capsule. Serogroups, A, B, C, D, X, Y, Z, 29E and W135 are responsible for virtually all cases of the human disease.

The carbohydrate component of the capsular membrane induces a T cell independent immune response, so neither long term immunity by memory cell formation nor antibody affinity maturation is observed. Rather than being engulfed and processed by an antigen presenting cell, the carbohydrate capsule interacts directly with B cells. This interaction causes production of serogroup specific antibodies, primarily IgM. IgG is also produced with an IgG1 response predominating in children and an IgG2 response predominating in adults.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Whole cell preparation of N. meningitidis types A, B and C
Preservative:
0.1% Sodium Azide (NaN3)

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.