Rabbit anti-NR1H4 Antibody

NR1H4 Polyclonal Antibody

$200.00  
144-08320-50
+

Antigen Information

Accession Number:
  • Q96RI1
Gene ID:
  • 9971
Gene Symbols:
  • NR1H4
Protein Name & Synonyms:
NR1H4, BAR, FXR, HRR-1, HRR1, PFIC5, RIP14, bile acid receptor
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Isotype:
IgG

Background

This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
48kDa/54kDa/55kDa
Observed MW
56kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 207-476 of human NR1H4 (NP_001193908.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using NR1H4 antibody (144-08320) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
Western blot - NR1H4 antibody (144-08320)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.