Rabbit anti-PACS1 Antibody

PACS1 pAb

$200.00  
144-62420-50
+

Antigen Information

Accession Number:
  • Q6VY07
Gene ID:
  • 55690
Gene Symbols:
  • PACS1
Protein Name & Synonyms:
PACS1, MRD17, SHMS, phosphofurin acidic cluster sorting protein 1
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human
Isotype:
IgG

Background

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.

Dilutions

WB 1:1000 - 1:3000

Format

Calculated MW
104kDa/109kDa
Observed MW
105kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 420-560 of human PACS1 (NP_060496.2).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.