Rabbit anti-PADI1 Antibody

PADI1 pAb

$320.00  
144-61746-100
+

Antigen Information

Accession Number:
  • Q9ULC6
Gene ID:
  • 29943
Gene Symbols:
  • PADI1
Protein Name & Synonyms:
PADI1, HPAD10, PAD1, PDI, PDI1, peptidyl arginine deiminase 1
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse
Isotype:
IgG

Background

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.

Dilutions

WB 1:200 - 1:1000

Format

Calculated MW
74kDa
Observed MW
65kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PADI1 (NP_037490.2).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.

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