Rabbit anti-PAK5 Antibody

PAK5 pAb

$200.00  
144-63954-50
+

Antigen Information

Accession Number:
  • Q9P286
Gene ID:
  • 57144
Gene Symbols:
  • PAK5
Protein Name & Synonyms:
PAK5, PAK7, p21 (RAC1) activated kinase 5
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse
Isotype:
IgG

Background

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
80kDa
Observed MW
81kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 600-700 of human PAK7 (NP_065074.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.