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Rabbit anti-PARD6A Antibody

PARD6A Polyclonal Antibody

$326.00  
144-03064-100
+ −

Antigen Information

Accession Number:
  • Q9NPB6
Gene ID:
  • 50855
Gene Symbols:
  • PARD6A
Protein Name & Synonyms:
PARD6A, PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40, partitioning defective 6 homolog alpha
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human,Mouse
Clonality:
Polyclonal
Isotype:
IgG

Background

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
37kDa
Observed MW
47kDa

Immunogen

A synthetic peptide of human PARD6A

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using PARD6A antibody (144-03064) at 1:200 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Western blot - PARD6A antibody (144-03064)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.

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