Protein Name & Synonyms:
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects ~70 kDa Perforin in samples from human, mouse and rat origins. Reactivity to other species has not been determined.
PFP, P1 , FLH2 , HPLH2, PRF1, Cytolysin , MGC65093
Human perforin (cytolysin) is believed to be one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Perforin expression is constitutive on NK cells, but increases in resting XD8+ cytotoxic cells upon activation.
Synthetic peptide surrounding amino acid 568 of rat Perforin
100 µg (0.5 mg/ml) affinity purified rabbit anti-Perforin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
-20 °C. The shelf life is 12 months.