Protein Name & Synonyms:
PI3, ESI, SKALP, WAP3, WFDC14, cementoin, elafin
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
IHC 1:50 - 1:200
Recombinant fusion protein containing a sequence corresponding to amino acids 23-117 of human PI3 (NP_002629.1).
Store at -20°. Avoid freeze / thaw cycles.