Rabbit Anti-PLC gamma 2 Antibody

Rabbit Anti-PLC gamma 2 Antibody , (100 ug)

$378.00  
168-10431
+

Antigen Information

Accession Number:
  • AAH18646
Protein Name & Synonyms:
PLC gamma 2

Antibody Specifications

Applications:
Western blotting (1-4 ug/ml), immunoprecipitation (20 ug/ml), and Immunohistochemistry (20 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 150 kDa PLCg2 in samples from human, mouse, and rat origins. The antibody does not cross-react with PLCg1.
Concentration:
0.5 mg/ml
Host Species:
Rabbit

Synonyms

PLC, EC 3.1.4.11 , Phosphoinositide phospholipase C , PLC-gamma-2 , Phospholipase C-gamma-2 , PLC-IV , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2

Description

PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCß, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.

Source

Immunogen
Synthetic peptide near the C-terminus of human PLCg2
Purification
Affinity purified

Format

Physical Appearance
Colorless liquid
Formulation
100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Specificity

PLCg2

Storage

-20 °C. The shelf life is 12 months.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.