Rabbit Anti-PLEKHF1 (N-term)

Rabbit Anti-PLEKHF1 (N-term) Antibody, 400 µl
CODE:  102-22340

Antigen Information

Accession Number:
  • NP_077286.3
  • Q96S99
Gene ID:
  • 79156
Gene Symbols:
  • PLEKHF1
Protein Name & Synonyms:
Pleckstrin homology domain-containing family F member 1, PH domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, Apoptosis-inducing protein, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing protein 15, PLEKHF1, APPD, LAPF, ZFYVE15

Antibody Specifications

Applications:
WB
Clone:
RB36045
Host Species:
Rabbit
Species Reactivity:
H
Clonality:
Polyclonal
Isotype:
Rabbit Ig

Introduction

PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.

Other Information

NCBI Accession #
NP_077286.3
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
31195
Antigen Source
Human

Images

WB (1:1000)

Anti-PLEKHF1 Antibody (N-term) at 1:1000 dilution + human heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 31 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

WB

Storage/Stability

2-8°C (short-term); -20°C (long-term)