Rabbit Anti-PPP2R4 (N-Term)

Rabbit Anti-PPP2R4 (N-Term) Antibody, 200 µl

$408.00  
102-25004
+

Antigen Information

Accession Number:
  • Q15257
Gene ID:
  • 5524
Gene Symbols:
  • PTPA
Protein Name & Synonyms:
Serine/threonine-protein phosphatase 2A activator, 5.2.1.8, PP2A, subunit B', PR53 isoform, Phosphotyrosyl phosphatase activator, PTPA, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B', PPP2R4, PTPA

Antibody Specifications

Applications:
WB
Clone:
RB54602
Host Species:
Rabbit
Species Reactivity:
H, M
Clonality:
Polyclonal
Isotype:
Rabbit Ig

Introduction

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.

Other Information

Antigen Type
Synthesized Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
40668
Antigen Source
Human

Images

WB (1:2000)

All lanes : Anti-PPP2R4 Antibody (N-Term) at 1:2000 dilution Lane 1: BA/F3 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: K562 whole cell lysate Lane 4: MCF-7 whole cell lysate Lane 5: Raji whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

WB

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.