Rabbit anti-PTGS1 Antibody

PTGS1 Polyclonal Antibody

$460.00  
144-07341-200
+

Antigen Information

Accession Number:
  • P23219
Gene ID:
  • 5742
Gene Symbols:
  • PTGS1
Protein Name & Synonyms:
PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, prostaglandin G/H synthase 1
Target Species:
  • Human

Antibody Specifications

Applications:
WB,IHC
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Isotype:
IgG

Background

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000
IHC 1:100 - 1:200

Format

Calculated MW
56kDa/61kDa/64kDa/68kDa/71kDa/72kDa
Observed MW
69kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PTGS1 (NP_001258094.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using PTGS1 antibody (144-07341) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 15s.
Western blot - PTGS1 antibody (144-07341)

Immunohistochemistry of paraffin-embedded human liver cancer using PTGS1 antibody (144-07341) at dilution of 1:100 (40x lens).
Immunohistochemistry - PTGS1 antibody (144-07341)

No posts found

Write A Review

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.

Recently Viewed Recently Viewed