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770-729-2992
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Product Specifications
Size:
0.15 ml
Protein Information
Protein Name & Synonyms:
GluR1 (pSer831)
Target Species:
- Rat
Antibody Specifications
Applications:
Western Blotting
Preparation:
Antisera to phosphorylated GluR1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by sequential affinity chromatography on phospho- and dephosphopeptide affinity columns.
Species Reactivity:
Rat, Human, mouse
This product detects a band of approximately 100 kDa in rat brain lysates.
Specificity
This antibody is specific for rat glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.
GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses.
Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses.
Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
Storage/Stability
Store at +4 °C or -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
10mM HEPES pH7.5
Format Type:
Purified
Preparation
Antisera to phosphorylated GluR1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by sequential affinity chromatography on phospho- and dephosphopeptide affinity columns.
Immunogen:
Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.
Preservative:
| 0.09% | Sodium Azide |
| 0.01% | Bovine Serum Albumin |
| 50% | Glycerol |
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
