Rabbit Anti-Rat Tyrosine Hydroxylase

Rabbit Anti-Rat Tyrosine Hydroxylase

$571.00
DS-PB-02045
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Antigen Information

Protein Name & Synonyms:
Tyrosine Hydroxylase
Target Species:
  • Rat

Antibody Specifications

Applications:
Immunohistology - Frozen, Immunofluorescence, Immunohistology - Paraffin, Western Blotting
Preparation:
Antisera to tyrosine hydroxylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Rat, Human and mouse

This product detects a band of approximately 60kDa in rat caudate cell lysates.

Specificity

This product is specific for Tyrosine hydroxylase (TH).

Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain.

Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
10mM HEPES pH7.5
Format Type:
Purified

Preparation

Antisera to tyrosine hydroxylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Tyrosine hydroxylase purified from pheochromocytoma.
Preservative:
0.09%Sodium Azide
0.01%Bovine Serum Albumin
50%Glycerol

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.