This product recognizes serotonin, also known as 5-hydroxytryptamine, or 5-HT. Serotonin is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin has broad activities in the brain. Genetic variation in serotonin receptors and the serotonin transporter (which facilitates reuptake of serotonin into presynapses) has been implicated in neurological diseases. Drugs targeting serotonin-induced pathways are being used in the treatment of many psychiatric disorders and one focus of clinical research is the influence of genetics on serotonin action and metabolism in psychiatric settings.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Antisera to serotonin were raised by repeated immunisation of rabbits with highly purified antigen. Whole serum is supplied.