Protein Name & Synonyms:
STK10, LOK, PRO2729, serine/threonine kinase 10
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 320-510 of human STK10 (NP_005981.3).
Store at -20°. Avoid freeze / thaw cycles.