Protein Name & Synonyms:
SULF1, SULF-1, sulfatase 1
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human SULF1 (NP_055985.2).
Store at -20°. Avoid freeze / thaw cycles.